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Article

MDR-1 and GST polymorphisms are involved in myelodysplasia progression.

Leukemia research - 1 Aug 2013

Palodetto Bruna, de Melo Campos Paula, Benites Bruno Deltreggia, de Lourdes Lopes Ferrari Chauffaille Maria, Velloso Elvira Deolinda Rodrigues Pereira, Traina Fabiola, Saad Sara Teresinha Olalla

Abstract excerpt

Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal stem cell disorders characterized by abnormal hematopoietic differentiation and maturation, which progress toward acute leukemia in approximately 30% of the cases. Drug metabolism polymorphisms in Cytochrome P450 2B6 (CYP2B6), Gl...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oxidoreductases, N-Demethylating

Source

Identifiers

PMID: 23684483
DOI: 10.1016/j.leukres.2013.04.024

Genes

GSTM1
NQO1
GSTT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23684483-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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