Article
Increased risk for myelodysplastic syndromes in individuals with glutathione transferase theta 1 (GSTT1) gene defect.
Lancet (London, England) - 3 Feb 1996
Chen H, Sandler D P, Taylor J A, Shore D L, Liu E, Bloomfield C D, Bell D A
Abstract excerpt
BACKGROUND: The glutathione S-transferases (GST) mediate exposure to various cytotoxic and genotoxic agents, including those associated with increased risk of the myelodysplastic syndromes (MDS). Both GST M1 (GSTM1) and GST theta 1 (GSTT1) genes have a "null" variant allele, in which the entire g...
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