Article
Formoterol Reduces the Pro-Inflammatory Phenotype by Enhancing the Activity of Glutaminase in Monocyte-Derived Macrophages in the CVB3-Induced Viral Myocarditis.
Immunity, inflammation and disease - 1 Nov 2024
Li Quan-Liang, Xie Hua-Bao, Guo Ying-Xin, Li Juan-Fen, Qian Jing, Wu Wei-Feng
Abstract excerpt
BACKGROUND: Viral myocarditis (VMC) plays a significant role in heart failure, and there is currently a shortage of available targeted treatments. Macrophage phenotype and function are closely associated with the beta-2 adrenergic receptor (β2-AR). METHOD: This research employed a BALB/c mouse model of VMC generated using Coxsackievirus B3 (CVB3), and the β2-AR agonist formoterol was administered as treatment. A...
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