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Article

IL-33 enhances macrophage M2 polarization and protects mice from CVB3-induced viral myocarditis.

Journal of molecular and cellular cardiology - 1 Feb 2017

Wang Chao, Dong Chunsheng, Xiong Sidong

Abstract excerpt

Viral myocarditis is the inflammation caused by myocardial virus infection, and the coxsackievirus group B3 virus (CVB3) is the most common pathogen. An efficient therapeutic agent against viral myocarditis is currently unavailable. IL-33, a new member of the IL-1 cytokine superfamily, exhibits potential immunotherapeutic effect against inflammatory and autoimmune diseases. However, the functional role of IL-33...

Topics

Adoptive Transfer
Animals
Biomarkers
Coxsackievirus Infections
Cytokines
Disease Models, Animal
Disease Susceptibility
Echocardiography
Enterovirus B, Human
Inflammation Mediators
Interleukin-33

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macrophages

Male

Mice

Myocarditis

Phenotype

Source

Identifiers

PMID: 28041873
DOI: 10.1016/j.yjmcc.2016.12.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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