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Article

Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.

Journal of molecular and cellular cardiology - 1 Jan 2017

Lynch Thomas L, Ismahil Mohamed Ameen, Jegga Anil G, Zilliox Michael J, Troidl Christian, Prabhu Sumanth D, Sadayappan Sakthivel

Abstract excerpt

Cardiomyopathies are a leading cause of heart failure and are often caused by mutations in sarcomeric genes, resulting in contractile dysfunction and cellular damage. This may stimulate the production of a robust proinflammatory response. To determine whether myocardial inflammation is associated with cardiac dysfunction in dilated cardiomyopathy (DCM) caused by MYBPC3 mutation, we used the well-characterized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27955979
DOI: 10.1016/j.yjmcc.2016.12.002
PMCID: PMC5316303

Genes

MYBPC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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