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Phenotypic Characterization of Subtype A and Recombinant AC Transmitted/Founder Viruses from a Rwandan HIV-1 Heterosexual Transmission Cohort.

Viruses - 30 Oct 2024

Yue Ling, Xu Rui, Mclnally Samantha, Qin Qianhong, Rhodes Jake W, Muok Erick, Umviligihozo Gisele, Brooks Kelsie, Zhang Jiayi, Qin Zhaohui, Bizimana Jean, Hare Jonathan, Price Matthew A, Allen Susan A, Karita Etienne, Hunter Eric

Abstract excerpt

HIV-1 subtypes have distinct geographical distributions, with subtypes A, C, and D and inter-subtype recombinants circulating in sub-Saharan Africa. Historically, individuals living with subtype A viruses exhibit slower CD4 decline and progression to AIDS diagnosis. Despite this, there are few authentic infectious molecular clones (IMCs) of subtype A or AC recombinant transmitted founder (TF) viruses with which...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39599821
DOI: 10.3390/v16111706
PMCID: PMC11599005

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