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Article

Evolutionary dynamics of HIV-1 recombinants: analysis of contemporary and historical viral populations in East Africa.

Virology journal - 17 Mar 2026

Balinda Sheila N, Kapaata Anne, Kato Frank, Nakyanzi Angella, Natwijuka Fortunate, Ndekezi Christian, Byamukama Drake, Omara Denis, Mugaba Susan, Obuku Andrew E, Salazar-Gonzalez Jesus F, Kaleebu Pontiano

Abstract excerpt

BACKGROUND: Understanding the genetic evolution of HIV-1 Transmitted/Founder (T/F) virus is crucial for developing effective treatment and prevention strategies due to its rapid mutation and recombination rates. METHODS: This study compared the genetic diversity of 24 contemporary T/F viruses collected between 2016 and 2021 in Uganda and Kenya with 29 historical T/F sequences sampled between 2006 and 2011....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41845497
DOI: 10.1186/s12985-026-03135-z
PMCID: PMC13113484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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