Article
Sequence Notes: Near Full-Length Genome Analysis of the First-Reported HIV-1 Circulating Recombinant Form (CRF)_10CD in Uganda.
AIDS research and human retroviruses - 1 Dec 2024
Bbosa Nicholas, Holzmayer Vera, Ssemwanga Deogratius, Downing Robert, Ssekagiri Alfred, Anderson Mark, Rodgers Mary A, Kaleebu Pontiano, Cloherty Gavin
Abstract excerpt
HIV-1 is characterized by remarkable genetic diversity resulting from its high replication rate, error-prone reverse transcriptase enzyme and recombination events. In Uganda, HIV-1 subtype diversity is mostly dominated by subtypes A, D, and A1/D Unique Recombinant Forms (URFs). In this study, deep sequences of HIV from patients with known antiretroviral therapy (ART) status were analyzed to determine the subtypes...
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