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Article

Gene Variant Frequencies of IDO1, IDO2, TDO, and KMO in Substance Use Disorder Cohorts.

Genes - 29 Oct 2024

Contella Lindsey, Farrell Christopher L, Boccuto Luigi, Litwin Alain, Snyder Marion L

Abstract excerpt

BACKGROUND: Substance use disorder in the United States represents a complex and growing public health crisis, marked by increasing rates of overdose deaths and the misuse of prescription medications. There is a critical need for furthering the understanding of the molecular and genetic mechanisms that can lead to substance use disorder. Identifying significant variants in the kynurenine pathway could help...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39596587
DOI: 10.3390/genes15111388
PMCID: PMC11594152

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