Article

Lactylation-Associated Prognostic Model and Role of ANLN in Pancreatic Ductal Adenocarcinoma

2025-09-09

Abstract excerpt

<title>Abstract</title> <p>Background Pancreatic ductal adenocarcinoma (PDAC) is a malignancy tumor with poor prognosis. Lactylation, a recently discovered post-translational protein modification, plays a critical role in tumor initiation and progression. Identifying reliable prognostic markers for PDAC is of significant clinical importance.This study aims to evaluate the prognostic impact of lactylation-associat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eb735e45-0558-5d2a-801b-6ce2caf21f60
DOI: 10.21203/rs.3.rs-6659167/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Lactylation-Associated Prognostic Model and Role of ANLN in Pancreatic Ductal AdenocarcinomaDOI 10.21203/rs.3.rs-6659167/v1Read

Novel lactylation-related signature to predict prognosis for pancreatic adenocarcinomaSemantic proximity Read

Establishment and Verification of a Novel Gene Signature Connecting Hypoxia and Lactylation for Predicting Prognosis and Immunotherapy of Pancreatic Ductal Adenocarcinoma Patients by Integrating Multi-Machine Learning and Single-Cell AnalysisSemantic proximity Read

Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinomaSemantic proximity Read

Lactate-associated gene MCU promotes the proliferation, migration, and invasion of pancreatic adenocarcinomaSemantic proximity Read

Comprehensive Genomic Analysis of the Prognostic and Immunological Characteristics of Tertiary Lymphoid structures and CD8+ T-cells in Pancreatic Ductal AdenocarcinomaSemantic proximity Read

PDAC-ANN: an artificial neural network to predict Pancreatic Ductal Adenocarcinoma based on gene expressionSemantic proximity Read

Molecular classification and prognosis study of pancreatic ductal adenocarcinoma through multi-omics integrated clustering analysis.Semantic proximity Read

Therapeutic trends in pancreatic ductal adenocarcinoma (PDAC)Semantic proximity Read

Gene expression profiling of 1200 pancreatic ductal adenocarcinoma reveals novel subtypesSemantic proximity Read

Development and validation of prognostic and diagnostic model for pancreatic ductal adenocarcinoma based on scRNA-seq and bulk-seq datasetsSemantic proximity Read

Constructing a lactylation-related genes prognostic model to effectively predict the disease-free survival and treatment responsiveness in prostate cancer based on machine learningSemantic proximity Read

PDAC-ANN: an artificial neural network to predict pancreatic ductal adenocarcinoma based on gene expressionSemantic proximity Read