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Article

Lympho-myeloid aggregate-infiltrating CD20+ B cells display a double-negative phenotype and correlate with poor prognosis in esophageal squamous cell carcinoma.

Translational research : the journal of laboratory and clinical medicine - 1 Jan 2025

Huang Qing-Feng, Wang Ge-Fei, Zhang Yi-Meng, Zhang Cong, Ran Ying-Qi, He Jian-Zhong, Wang Geng, Xu Xiu-E, Wang Shao-Hong, Wu Jian-Yi, Li En-Min, Xu Li-Yan

Abstract excerpt

According to morphological features, tumor-infiltrating B cells (TIL-Bs) can be classified as lympho-myeloid aggregates (LMAs) and tertiary lymphoid structures (TLSs). As a disease with high incidence and mortality, research on esophageal squamous cell carcinoma (ESCC) TIL-Bs is still unclear. Thus, we aimed to investigate the prognostic value and functional involvement of TIL-Bs in ESCC. Based on CD20...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39536938
DOI: 10.1016/j.trsl.2024.11.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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