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Article

Phenotypic profiling and prognostic significance of immune infiltrates in esophageal squamous cell carcinoma

1 Jan 2021

Abstract excerpt

The tumor microenvironment (TME) of esophageal squamous cell carcinoma (ESCC) impacts tumor progression but is poorly understood. We obtained tumor tissues from 279 patients after esophagectomy and characterized the TME in intraepithelial and stromal regions using multiplex fluorescent immunohistochemistry (mfIHC). A heterogeneous immune population infiltrating tumor and the uninvolved esophageal tissue were...

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PMID: 33628625
DOI: 10.1080/2162402x.2021.1883890

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