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Article

When more sugar is better-a GPI side chain modification results in a less virulent phenotype during a protozoan infection.

mBio - 11 Dec 2024

Seeber Frank

Abstract excerpt

The assembly and function of side chain modifications of glycosylphosphatidylinositol (GPI) units (anchors or free forms) are poorly defined. In a recent study, two enzymes, PIGJ and PIGE, of the protozoan parasite Toxoplasma gondii were identified and shown to be involved in the assembly of such GPI side chains (J. A. Alvarez, E. Gas-Pascual, S. Malhi, J. C. Sánchez-Arcila, et al., mBio 15:e00527-24, 2024,...

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Identifiers

PMID: 39535216
DOI: 10.1128/mbio.02740-24
PMCID: PMC11633089

Genes

GPI
CD36

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

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When more sugar is better-a GPI side chain modification results in a less virulent phenotype during a protozoan infection.PMID 39535216Read ↗

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