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Diverse antifungal potency of terbinafine as a therapeutic agent against Exophiala dermatitidis in vitro

11 Nov 2024

Abstract excerpt

Exophiala dermatitidis ( E. dermatitidis ), which causes skin or respiratory disease, is occasionally fatal in immunocompromised patients. Here, we report the unique antifungal potency of terbinafine (TRB), which targets squalene epoxidase, against E. dermatitidis (SQLE ED ) using various in vitro approaches. The versatile antifungal activities, including fungicidal activity, biofilm formation inhibition, biofilm...

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PMID: 39528542
DOI: 10.1038/s41598-024-78815-3

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