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Antifungal potency of terbinafine as a therapeutic agent against Exophiala dermatitidis in vitro

2024-05-25

Abstract excerpt

<h4>Background: </h4> Exophiala dermatitidis (E. dermatitidis), which causes skin infections or respiratory diseases, is occasionally fatal in immunocompromised patients. <h4>Objectives:</h4> Here, we report the unique antifungal potency of terbinafine (TRB), which targets squalene epoxidase, against E. dermatitidis (SQLEED) using various in vitro approaches. <h4>Methods:</h4> Based on the human SQLE crystal struc...

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Identifiers and source

Literature Corpus work
7494bcad-a453-5b29-aca3-bb06368882ce
DOI
10.1101/2024.05.25.595862
Open publication

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Antifungal potency of terbinafine as a therapeutic agent against Exophiala dermatitidis in vitroDOI 10.1101/2024.05.25.595862
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