Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical Management of Antifungal-Resistant Dermatophytosis in Japan.

Medical mycology journal - 1 Jan 2026

Noguchi Hiromitsu, Kano Rui

Abstract excerpt

Dermatophytosis remains one of the most common superficial fungal infections worldwide, and antifungal-resistant strains have recently emerged as an increasing clinical concern. In Japan, the prevalence of terbinafine-resistant Trichophyton species is currently estimated to be 2%, with most isolates harboring squalene epoxidase (SQLE) gene mutations such as Leu393Phe and Phe397Leu. This review summarizes recent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal Agents
Share to Arthrodermataceae
Share to Drug Resistance, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Imidazoles

Share to Triazoles

Share to Trichophyton

Source

Identifiers

PMID: 42219346
DOI: 10.3314/mmj.26.009

Genes

SQLE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical Management of Antifungal-Resistant Dermatophytosis in Japan.PMID 42219346Read ↗

Increased terbinafine resistance among clinical genotypes of Trichophyton mentagrophytes/T. interdigitale species complex harboring squalene epoxidase gene mutations.Semantic proximity Read ↗

Terbinafine‐resistant strain of Trichophyton interdigitale strain isolated from a tinea pedis patientSemantic proximity Read ↗

First Terbinafine-Resistant Trichophyton indotineae Isolates with Phe397Leu and/or Thr414His Mutations in Turkey.Semantic proximity Read ↗

Antifungal potency of terbinafine as a therapeutic agent against Exophiala dermatitidis in vitroSemantic proximity Read ↗

Emergence of Terbinafine Resistant Trichophyton mentagrophytes in Iran, Harboring Mutations in the Squalene Epoxidase (SQLE) GeneSemantic proximity Read ↗

Terbinafine-resistant T. indotineae due to F397L/L393S or F397L/L393F mutation among corticoid-related tinea incognita patients.Semantic proximity Read ↗

Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in ThailandSemantic proximity Read ↗

Mutation in the Squalene Epoxidase Gene of Trichophyton interdigitale and Trichophyton rubrum Associated with Allylamine ResistanceSemantic proximity Read ↗

Phylogeny, Antifungal Susceptibility, and Point Mutations of SQLE Gene in Major Pathogenic Dermatophytes Isolated From Clinical DermatophytosisSemantic proximity Read ↗

Prolonged treatment of dermatophytosis caused by Trichophyton indotinea with terbinafine or itraconazole impacts better outcomes irrespective of mutation in the squalene epoxidase gene.Semantic proximity Read ↗

Evaluation of DermaGenius ® resistance real‐time polymerase chain reaction for rapid detection of terbinafine‐resistant Trichophyton speciesSemantic proximity Read ↗

Molecular Characterization and Preliminary NGS Profiling of Terbinafine-Resistant Trichophyton indotineae Isolates in Italy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.