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Terbinafine resistance is associated with newly developed point mutations in squalene epoxidase gene in Trichophyton rubrum and T. mentagrophytes/T. indotineae species complex

2023-06-06

Abstract excerpt

The prevalence of dermatophytosis has increased in recent years due to a rise in resistance of etiologic dermatophytes to terbinafine which could be attributed in part to point mutation in the squalene epoxidase ( SQLE ) gene. In this study, the point mutation in the SQLE gene was studied in Trichophyton rubrum and T. mentagrophytes/T. indotineae species complex as two main causative agents of dermatophytosis. Ant...

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Literature Corpus work
e6998326-725d-5643-bab1-f3189fd17a49
DOI
10.21203/rs.3.rs-3003123/v1
Open publication

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Terbinafine resistance is associated with newly developed point mutations in squalene epoxidase gene in Trichophyton rubrum and T. mentagrophytes/T. indotineae species complexDOI 10.21203/rs.3.rs-3003123/v1
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