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Article

Detection of Squalene Epoxidase Mutations in United States Patients with Onychomycosis: Implications for Management.

The Journal of investigative dermatology - 1 Dec 2023

Gupta Aditya K, Cooper Elizabeth A, Wang Tong, Polla Ravi Shruthi, Lincoln Sara A, Piguet Vincent, McCarthy Laurence R, Bakotic Wayne L

Abstract excerpt

Resistance to oral terbinafine, the most commonly used antifungal to treat dermatophytosis and onychomycosis worldwide, is being increasingly reported. In this study, we aimed to investigate the species distribution and prevalence of squalene epoxidase mutations among toenail dermatophyte isolates. Samples from 15,683 patients suspected of onychomycosis visiting the offices of dermatologists and podiatrists in...

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Identifiers

PMID: 37236595
DOI: 10.1016/j.jid.2023.04.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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