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Article

Increased terbinafine resistance among clinical genotypes of Trichophyton mentagrophytes/T. interdigitale species complex harboring squalene epoxidase gene mutations.

Journal de mycologie medicale - 1 Sept 2024

Mohammadi Leila Zahedi, Shams-Ghahfarokhi Masoomeh, Salehi Zahra, Razzaghi-Abyaneh Mehdi

Abstract excerpt

Terbinafine resistance has become epidemic as an emerging problem in treatment of dermatohpytosis. This could be attributed in part to a point mutation in the squalene epoxidase (SQLE) gene. In this study, point mutations in the SQLE gene were studied in T. rubrum and T. mentagrophytes/T. interdigitale species complex as two main causative agents of dermatophytosis. Antifungal susceptibility of clinical isolates...

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PMID: 38896927
DOI: 10.1016/j.mycmed.2024.101495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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