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Article

[Mutation process and malignant transformation induced by adenoviruses in mammalian cells].

TSitologiia i genetika - 1 Jan 2000

Lukash L L

Abstract excerpt

Both oncogenic adenovirus (BAV-3) and nononcogenic adenovirus (Ad-1) are able to induce gene mutations in cultured mammalian cells. In the case of equal multiplicity of the infection the frequency of induced mutations is higher in variants with Ad-1. Unlike Ad-1 both mutagenic and transforming effects of BAV-3 are intensified by means of TPA promoters. TPA modifies analogously mutagenic and transforming effect of...

Topics

Adenoviridae
Adenoviruses, Human
Animals
Cell Transformation, Neoplastic
Cell Transformation, Viral
Cells, Cultured
Cocarcinogenesis
Cricetinae
Cricetulus
DNA, Viral
Mice
Mice, Inbred C3H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Tetradecanoylphorbol Acetate

Transfection

Source

Identifiers

PMID: 3952810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3952810-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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