Article
[Induction of unstable mutations in Drosophila melanogaster by microinjection of oncogenic virus DNA into polar embryonic plasm. Malignant effect of oncoviral DNA].
Genetika - 1 May 1991
Nabirochkin S D, Gabitova L B, Begetova T V, Gazarian K G
Abstract excerpt
We have demonstrated that the ability to induce benign neoplasms We have dominant mode of inheritance in Drosophila melanogaster is the specific feature of oncoviral DNAs. It is supposed that development of this type of neoplasms in Drosophila is connected with the changes in expression of protooncogenes in mutant genome: firstly, the genetic factors directing the development of neoplasms and Drosophila...
Topics
- Animals
- Blotting, Southern
- DNA, Viral
- Drosophila melanogaster
- Genes, Viral
- Microinjections
- Mutation
- Neoplasms, Experimental
- Oncogenic Viruses
- Proto-Oncogenes