Article
[The mutagenic action of the DNA fragments of bovine adenovirus type 3 (BAV-3) containing early E1 (oncogene) and E4 regions].
Izvestiia Akademii nauk SSSR. Seriia biologicheskaia - 1 Jan 2000
Charikova E V
Abstract excerpt
A study of mutagenic action of DNA fragments of bovine adenovirus type 3 (BAV-3), containing early E1 (oncogenic) and E4 regions has been carried out. Viral DNA was digested with Xba 1 restriction endonuclease. The mutagenic effect revealed itself by induction of resistance to 6-mercaptopurine in Chinese hamster cells. The data obtained suggest that the early regions E1 and E4 can cause mutagenic effect in...
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