[Presence of specific mutation of Ha-ras oncogene in skin tumors of mice induced under different experimental conditions].

Article

[Presence of specific mutation of Ha-ras oncogene in skin tumors of mice induced under different experimental conditions].

Biulleten' eksperimental'noi biologii i meditsiny - 1 Apr 1991

Loktionov A S, Popovich I G, Zabezhinskiĭ M A, Anisimov V N

Abstract excerpt

The mutation was revealed with substitution of A for T in the second position of the 61 Ha-ras oncogene codon in the DNA of 31 skin tumours (26 papillomas and 5 carcinomas) and in 23 mice treated with 12-O-tetradecanoyl phorbol-13-acetate (TPA). Part of these mice were F progeny (n-6) and F proge...

Topics

9,10-Dimethyl-1,2-benzanthracene
Animals
Carcinoma
Codon
Female
Genes, ras
Male
Mice
Mutation
Papilloma
Pregnancy
Skin Neoplasms
Tetradecanoylphorbol Acetate

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.