Article
[Presence of specific mutation of Ha-ras oncogene in skin tumors of mice induced under different experimental conditions].
Biulleten' eksperimental'noi biologii i meditsiny - 1 Apr 1991
Loktionov A S, Popovich I G, Zabezhinskiĭ M A, Anisimov V N
Abstract excerpt
The mutation was revealed with substitution of A for T in the second position of the 61 Ha-ras oncogene codon in the DNA of 31 skin tumours (26 papillomas and 5 carcinomas) and in 23 mice treated with 12-O-tetradecanoyl phorbol-13-acetate (TPA). Part of these mice were F progeny (n-6) and F progeny (n-4) following DMBA administration during pregnancy, another part F progeny (n-5) following ENU action on males...
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