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TRIM32 inhibits Venezuelan equine encephalitis virus infection by targeting a late step in viral entry

11 Nov 2024

Abstract excerpt

Alphaviruses are mosquito borne RNA viruses that are a reemerging public health threat. Alphaviruses have a broad host range, and can cause diverse disease outcomes like arthritis, and encephalitis. The host ubiquitin proteasome system (UPS) plays critical roles in regulating cellular processes to control the infections with various viruses, including alphaviruses. Previous studies suggest alphaviruses hijack UPS...

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PMID: 39527628
DOI: 10.1371/journal.ppat.1012312

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