Causal Association Between Heart Failure and Sepsis: Insights from Mendelian Randomization and Observational Studies

Abstract excerpt

Purpose: We aimed to identify the association between heart failure (HF) with sepsis and its mortality through Mendelian randomization (MR) and observational studies. Patients and Methods: In MR study, we utilized public summary statistics from genome-wide association studies (GWAS). We conducted univariable, multivariable and network MR analyses to investigate causal relationships between HF and sepsis, and...

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