Article
Causal associations between polyunsaturated fatty acids and kidney function: A bidirectional Mendelian randomization study.
The American journal of clinical nutrition - 1 Jan 2023
Huang Yingyue, Wang Jiao, Yang Huiling, Lin Zihong, Xu Lin
Abstract excerpt
BACKGROUND: PUFAs were suggested to be beneficial for kidney function in observational studies. However, whether these associations are causal remains unclear. OBJECTIVES: This study explores the causality between PUFAs and chronic kidney disease (CKD) or estimated glomerular filtration rate (eGFR) using bidirectional 2-sample Mendelian randomization (MR). METHODS: Single nucleotide polymorphisms associated with...
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