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Micronutrients and Major Depression: A Mendelian Randomisation Study.

Nutrients - 29 Oct 2024

Carnegie Rebecca E, Zheng Jie, Borges Maria C, Jones Hannah J, Wade Kaitlin H, Sallis Hannah M, Lewis Sarah J, Evans David M, Revez Joana A, The Major Depressive Disorder Working Group Of The Psychiatric Genomics Consortium, Evans Jonathan, Martin Richard M

Abstract excerpt

BACKGROUND: Various vitamins and minerals have been implicated in the aetiology of depression. OBJECTIVE: To estimate the effects of micronutrient exposures on major depressive disorder (MDD) and recurrent depression (rMDD) using Mendelian randomisation (MR), a method using genetic data to estimate causal effects given certain assumptions. METHODS: We undertook a comprehensive bidirectional MR study of multiple...

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PMID: 39519523
DOI: 10.3390/nu16213690
PMCID: PMC11547740

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