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Article

Relationship between Serum 25(OH)D and Depression: Causal Evidence from a Bi-Directional Mendelian Randomization Study.

Nutrients - 30 Dec 2020

Mulugeta Anwar, Lumsden Amanda, Hyppönen Elina

Abstract excerpt

The relationship between depression and vitamin D deficiency is complex, with evidence mostly from studies affected by confounding and reverse causality. We examined the causality and direction of the relationship between 25-hydroxyvitamin D (25(OH)D) and depression in bi-directional Mendelian randomization (MR) analyses using information from up to 307,618 white British participants from the UK Biobank and...

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PMID: 33396887
DOI: 10.3390/nu13010109
PMCID: PMC7823924

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