The Potential Role of Serum Iron in Depression: Further Exploration of Future Research Directions.

Abstract excerpt

BACKGROUND: Depressive disorder (DD) is a common affective disorder with an unclear specific etiology. Although many previous studies have suggested that iron metabolism is involved in the development of DD, there is a lack of validated genetic evidence regarding whether iron metabolism-related indices (i.e., total iron binding capacity, transferrin saturation, ferritin, and serum iron) are causally related to...

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