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A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics

5 Sept 2019

Abstract excerpt

Trials testing the effect of vitamin D or omega-3 polyunsaturated fatty acid (n3-PUFA) supplementation on major depressive disorder (MDD) reported conflicting findings. These trials were inspired by epidemiological evidence suggesting an inverse association of circulating 25-hydroxyvitamin D (25-OH-D) and n3-PUFA levels with MDD. Observational associations may emerge from unresolved confounding, shared genetic...

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PMID: 31488809
DOI: 10.1038/s41398-019-0554-y

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