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Article

Compression force promotes glioblastoma progression through the Piezo1‑GDF15‑CTLA4 axis

30 Oct 2024

Abstract excerpt

Glioma, a type of brain tumor, is influenced by mechanical forces in its microenvironment that affect cancer progression. However, our understanding of the contribution of compression and its associated mechanisms remains limited. The objective of the present study was to create an environment in which human brain glioma H4 cells experience pressure and thereby investigate the compressive mechanosensors and...

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Identifiers

PMID: 39513613
DOI: 10.3892/or.2024.8835

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