Article
Genetic and Biological Effects of ICAM-1 E469K Polymorphism in Diabetic Kidney Disease.
Journal of diabetes research - 1 Jan 2020
Zhang Xiuli, Seman Norhashimah Abu, Falhammar Henrik, Brismar Kerstin, Gu Harvest F
Abstract excerpt
Diabetic kidney disease (DKD) is a complex disease, in which local inflammatory stress results from both metabolic and hemodynamic derangements. Intercellular adhesion molecule 1 (ICAM-1) is an acute-phase protein marker of inflammation. In the recent years, clinical observations have reported that increased serum/plasma ICAM-1 levels are positively correlated with albuminuria in the patients with type 1 (T1D)...
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