Article
Association of long noncoding RNA GAS5 gene polymorphism with progression of diabetic kidney disease.
International journal of medical sciences - 1 Jan 2024
Yang Po-Jen, Ting Ke-Hsin, Tsai Po-Yu, Su Shih-Chi, Yang Shun-Fa
Abstract excerpt
Diabetic kidney disease (DKD) is a common microvascular complication of diabetes, whose complex etiology involves a genetic component. Growth arrest-specific 5 (GAS5), a long noncoding RNA (lncRNA) gene, has been recently shown to regulate renal fibrosis. Here, we aimed to explore the potential role of GAS5 gene polymorphisms in the predisposition to DKD. One single-nucleotide (rs55829688) and one...
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