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Article

Low nucleotide diversity of the Plasmodium falciparum AP2-EXP2 gene among clinical samples from Ghana.

Parasites & vectors - 5 Nov 2024

Quansah Elvis, Zhao Ji, Eduful Kenneth Kofi, Amoako Enock Kofi, Amenga-Etego Lucas, Halm-Lai Faustina, Luo Qingli, Shen Jilong, Zhang Chao, Yu Li

Abstract excerpt

BACKGROUND: PfAP2-EXP2 is located within chromosome 6 of Plasmodium falciparum recently identified to be undergoing an extensive selective sweep in West African isolates. The gene encoding this transcription factor, PfAP2-EXP2, is essential and thus likely subject to purifying selection that limits variants in the parasite population despite its genomic location. METHODS: 72 Plasmodium falciparum field samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39501336
DOI: 10.1186/s13071-024-06545-6
PMCID: PMC11539609

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