Article
Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates.
Parasites & vectors - 12 Mar 2018
Adams Tryphena, Ennuson Nana Aba A, Quashie Neils B, Futagbi Godfred, Matrevi Sena, Hagan Oheneba C K, Abuaku Benjamin, Koram Kwadwo A, Duah Nancy O
Abstract excerpt
BACKGROUND: Plasmodium falciparum delayed clearance with the use of artemisinin-based combination therapy (ACTs) has been reported in some African countries. Single nucleotide polymorphisms (SNPs) in two genes, P. falciparum adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1), have been linked to delayed clearance with ACT use in Kenya and recurrent imported malaria in...
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