Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diversity of the sarco/endoplasmic reticulum Ca(2+)-ATPase orthologue of Plasmodium falciparum (PfATP6).

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 May 2008

Dahlström Sabina, Veiga Maria Isabel, Ferreira Pedro, Mårtensson Andreas, Kaneko Akira, Andersson Björn, Björkman Anders, Gil José Pedro

Abstract excerpt

The sarco/endoplasmic reticulum Ca(2+)-ATPase orthologue of Plasmodium falciparum (PfATP6) has been suggested to be involved in the mechanism of action and resistance to artemisinins, the main constituent of artemisinin-based combination therapy (ACT). In previous studies only six single-nucleotide polymorphisms (SNPs) have been described in clinical samples and field isolates. Our aim was to sequence a large...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Artemisinins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcium-Transporting ATPases

Share to Lactones

Share to Malaria, Falciparum

Share to Sarcoplasmic Reticulum Calcium-Transporting ATPases

Share to Sesquiterpenes

Share to Tanzania

Source

Identifiers

PMID: 18359278
DOI: 10.1016/j.meegid.2008.02.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diversity of the sarco/endoplasmic reticulum Ca(2+)-ATPase orthologue of Plasmodium falciparum (PfATP6).PMID 18359278Read ↗

Characterization of the Plasmodium falciparum sarcoplasmic/endoplasmic reticulum Ca2+-ATPase gene in samples from Equatorial Guinea before implementation of artemisinin-based combination therapy.Semantic proximity Read ↗

Spontaneous mutations in the Plasmodium falciparum sarcoplasmic/ endoplasmic reticulum Ca2+-ATPase (PfATP6) gene among geographically widespread parasite populations unexposed to artemisinin-based combination therapies.Semantic proximity Read ↗

Pfatp6 molecular profile of Plasmodium falciparum isolates in the western Brazilian Amazon.Semantic proximity Read ↗

Genetic diversity and lack of artemisinin selection signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion.Semantic proximity Read ↗

Geographic structuring of the Plasmodium falciparum sarco(endo)plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity.Semantic proximity Read ↗

Molecular assessment of atpase6 mutations associated with artemisinin resistance among unexposed and exposed Plasmodium falciparum clinical isolates to artemisinin-based combination therapy.Semantic proximity Read ↗

Brazilian Plasmodium falciparum isolates: investigation of candidate polymorphisms for artemisinin resistance before introduction of artemisinin-based combination therapy.Semantic proximity Read ↗

Plasmodium malariae structure and genetic diversity in sub-Saharan Africa determined from microsatellite variants and linked SNPs in orthologues of antimalarial resistance genes.Semantic proximity Read ↗

Plasmodium malariae structure and genetic diversity in sub-Saharan Africa determined from microsatellite variants and linked SNPs in orthologues of antimalarial resistance genesSemantic proximity Read ↗

Molecular epidemiology of malaria in Cameroon. XXVIII. In vitro activity of dihydroartemisinin against clinical isolates of Plasmodium falciparum and sequence analysis of the P. falciparum ATPase 6 gene.Semantic proximity Read ↗

Plasmodium falciparum multidrug resistance protein 1 and artemisinin-based combination therapy in Africa.Semantic proximity Read ↗

Genetic diversity of Plasmodium falciparum equilibrative nucleoside transporters PfENT1 and PfENT4: Implications for purine-based antimalarial drug development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.