Article
The genomic landscape of papillary thyroid carcinoma on next-generation sequencing in patients undergoing total thyroidectomy.
World journal of surgery - 1 Dec 2024
Poongkodi Karunakaran, Periyasamy Sumathi, Gurunathan Raj Ashok, Krishnasamy Vijayakumar, Jayakumar Deepak, Subburaman Ramesh, Jayaraman Sujatha, Prabhudas Sudheesh K
Abstract excerpt
BACKGROUND: Thyroidectomy is increasingly performed for suspected malignancy. This cohort study aimed to identify genetic markers associated with malignancy and determine the molecular landscape of papillary thyroid carcinoma (PTC) through next-generation sequencing (NGS) in patients undergoing total thyroidectomy. PATIENTS AND METHODS: Among 116 surgical candidates, 103 patients (age = 42.9 ± 13.7 years; Male:...
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