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Article

Utilities of next-generation sequencing in the surgical management of thyroid nodules in China.

BMC endocrine disorders - 5 Mar 2026

Lin Kaige, Xin Xuan, Liu Jinge, Shi Fuyun, Zheng Luming, He Qingqing, Ma Yunhan

Abstract excerpt

This study aimed to evaluate the diagnostic utility of next-generation sequencing (NGS) for identifying genetic alterations in fine-needle aspiration (FNA) samples from thyroid nodules, with a specific focus on its clinical implications for surgical management. In total, 631 patients underwent FNA cytology, yielding 683 cytological samples. Of these, 264 patients with indeterminate or suspicious cytological...

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Source

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Identifiers

PMID: 41787459
DOI: 10.1186/s12902-026-02200-6
PMCID: PMC13072540

Genes

BRAF
TERT
TP53

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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