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Genetic characteristics and response to systemic therapies of acral lentiginous melanoma at a tertiary care center-a retrospective review.

Journal of the National Medical Association - 1 Feb 2022

Jamerson Taylor, Rebecca Vito W, Aguh Crystal

Abstract excerpt

BACKGROUND: Acral lentiginous melanoma (ALM) is an aggressive subtype of cutaneous malignant melanomas that accounts for 50-80% of melanomas in ethnic minorities. Studies on the genetic profile of these tumors largely result from cohorts in Europe, Asia, and Latin America, few inclusive of Black patients. OBJECTIVE: We aim to describe the clinicopathological and genetic characteristics in a diverse cohort of ALM...

Topics

Humans
Melanoma
Mutation
Prognosis
Retrospective Studies
Skin Neoplasms
Tertiary Care Centers

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34509302
DOI: 10.1016/j.jnma.2021.08.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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