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Article

Relationship between inflammation/immunity and epilepsy: A multi-omics mendelian randomization study integrating GWAS, eQTL, and mQTL data.

Epilepsy & behavior : E&B - 1 Dec 2024

Mu Jing, Cao Changqing, Gong Yigu, Hu Guiying

Abstract excerpt

OBJECTIVES: Increasing evidence suggests that activated innate/adaptive immunity induces an inflammatory response, thereby participating in epileptogenesis. However, the biological explanation of inflammation/immunity as a potential cause for epilepsy remains largely unknown. This research aimed to determine the causal effects of inflammation/immune-related genes in epilepsy based on multi-omics mendelian...

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PMID: 39467451
DOI: 10.1016/j.yebeh.2024.110112

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