Article
Causal associations between gut microbiota, circulating inflammatory proteins, and epilepsy: a multivariable Mendelian randomization study.
Frontiers in immunology - 1 Jan 2024
Yang Han, Liu Wei, Gao Tiantian, Liu Qifan, Zhang Mengyuan, Liu Yixin, Ma Xiaodong, Zhang Nan, Shi Kaili, Duan Minyu, Ma Shuyin, Zhang Xiaodong, Cheng Yuxuan, Qu Huiyang, Chen Mengying, Zhan Shuqin
Abstract excerpt
Background: Previous studies have suggested that gut microbiota (GM) may be involved in the pathogenesis of epilepsy through the microbiota-gut-brain axis (MGBA). However, the causal relationship between GM and different epilepsy subtypes and whether circulating inflammatory proteins act as mediators to participate in epileptogenesis through the MGBA remain unclear. Therefore, it is necessary to identify specific...
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