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Article

Investigating the causal relationship between circulating inflammatory proteins and tinnitus: Insights from a Mendelian Randomization study.

Hearing research - 1 Sept 2025

He Shichun, Wei Meiqi, Meng Deyu, Lv Zongnan, Yang Guang, Wang Ziheng

Abstract excerpt

Tinnitus, a condition characterized by the perception of ringing in the ears, significantly impacts quality of life, yet its underlying biological mechanisms remain poorly understood. Emerging evidence suggests a role for inflammation in tinnitus pathophysiology. This study employs a bidirectional two-sample Mendelian Randomization (MR) approach to investigate the causal relationship between circulating...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 40651217
DOI: 10.1016/j.heares.2025.109300

Genes

CCL19
CXCL11
TNFSF12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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