Article

The ABCD-GENE score influences vascular event rates in both users of clopidogrel and aspirin, as well as non-users of either drug in a population-based cohort study

2023-08-09

Abstract excerpt

<h4>Background and Objectives</h4> Clopidogrel is an antiplatelet used in both primary and secondary prevention of cardiovascular diseases. It is a prodrug, requiring CYP2C19 for its metabolism to the active metabolite. The ABCD-GENE score, combining clinical attributes (age, body mass index, chronic kidney disease, diabetes mellitus), with genetic information (presence of 1 or 2 loss of function (LOF) alleles in...

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Literature Corpus work: f0ca6d9d-a212-5305-a297-2add8ba57dab
DOI: 10.1101/2023.08.06.23293732

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