Article
Cardiovascular pharmacogenomics: current status and future directions.
Journal of human genetics - 1 Jan 2016
Roden Dan M
Abstract excerpt
Drugs are widely used and highly effective in the treatment of heart disease. Nevertheless, in some instances, even drugs effective in a population display lack of efficacy or adverse drug reactions in individual patients, often in an apparently unpredictable fashion. This review summarizes the genomic factors now known to influence variability in responses to widely used cardiovascular drugs such as clopidogrel,...
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