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Article

Distribution of lineages and type II toxin-antitoxin systems among rifampin-resistant Mycobacterium Tuberculosis Isolates.

PloS one - 1 Jan 2024

Shafipour Maryam, Mohammadzadeh Abdolmajid, Mahmoodi Pezhman, Dehghanpour Mahdi, Ghaemi Ezzat Allah

Abstract excerpt

Type II toxin-antitoxin systems such as mazEF3, vapBC3, and relJK play a role in antibiotic resistance and tolerance. Among the different known TA systems, mazEF3, vapBC3, and relJK, which are type II systems, have specific roles in drug resistance. Therefore, the aim of this study was to investigate the mutations in these genes in sensitive and resistant isolates of Mycobacterium tuberculosis. Thirty-two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39446830
DOI: 10.1371/journal.pone.0309292
PMCID: PMC11500941

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