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Genomic Polymorphisms in Toxin-Antitoxin Systems and Identification of Novel Phylo-SNPs and Polymorphisms Associated with Drug Resistance/Susceptibility in Clinical Isolates of <i>Mycobacterium tuberculosis</i> from Mumbai, India

2019-10-08

Abstract excerpt

<h4>ABSTRACT</h4> Toxin-antitoxin (TA) modules are one of the prominent determinants that triggers a persistent state aiding Mycobacterium tuberculosis evasion to host generated stresses. The 79 characterized and putative TA systems described in M. tuberculosis are dominated by the VapBC, MazEF, HigAB, RelBE and ParDE TA families, largely involved in persistence and cell arrest. Hence, there is a need to mainta...

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Literature Corpus work
e2c714c4-6c70-508d-bf28-d4b370dc034a
DOI
10.1101/797274
Open publication

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Genomic Polymorphisms in Toxin-Antitoxin Systems and Identification of Novel Phylo-SNPs and Polymorphisms Associated with Drug Resistance/Susceptibility in Clinical Isolates of <i>Mycobacterium tuberculosis</i> from Mumbai, IndiaDOI 10.1101/797274
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