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Article

Comparative analysis of drug susceptibility among different Mycobacterium abscessus morphotypes.

BMC microbiology - 26 Dec 2025

Cheng Kai, Guo Jiaying, Shang Yuanyuan, Ren Weicong, Zhao Weijie, Li Shanshan

Abstract excerpt

BACKGROUND: Mycobacterium abscessus (MAB), a rapidly growing non-tuberculous mycobacterium, presents severe therapeutic challenges due to its intrinsic and acquired multidrug resistance. Notably, MAB exhibits phenotypic heterogeneity, with smooth (S) and rough (R) morphotypes displaying distinct drug susceptibility phenotypes. RESULTS: We systematically examined the phenotypic diversity and drug susceptibility...

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Identifiers

PMID: 41449347
DOI: 10.1186/s12866-025-04627-8
PMCID: PMC12882414

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