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Article

A novel genetic association of IL32 with tuberculosis.

Cytokine - 1 Dec 2024

Gautam Anuradha, Bhattacharyya Chandrika, Dasgupta Ahana, Bhattacharjee Samsiddhi, Pandit Bhaswati

Abstract excerpt

AIM: IL32 is a pleiotropic intracellular cytokine with an emergent role in tuberculosis. The different isoforms of IL32: α, β, γ and δ have varying pro and anti-inflammatory potentials. We studied the role of genetic variants of IL32 and its isoforms in susceptibility to tuberculosis using a case-household contact association study. METHODOLOGY: Using a targeted sequencing approach, IL32 (+1kb) gene was sequenced...

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Source

Identifiers

PMID: 39442340
DOI: 10.1016/j.cyto.2024.156783

Genes

IL32
BICDL2

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