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Article

A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma.

Carcinogenesis - 1 Jul 2013

Plantinga Theo S, Costantini Irene, Heinhuis Bas, Huijbers Angelique, Semango George, Kusters Benno, Netea Mihai G, Hermus Ad R M M, Smit Jan W A, Dinarello Charles A, Joosten Leo A B, Netea-Maier Romana T

Abstract excerpt

Interleukin (IL)-32 is an intracellular proinflammatory mediator that strongly modulates the inflammatory reaction. Recent studies have suggested the involvement of IL-32 in the pathogenesis of malignancies. We aimed to assess whether a known germ-line polymorphism in the IL32 promoter modulates...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23486016
DOI: 10.1093/carcin/bgt092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23486016-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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