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Article

Fulminant leptomeningeal disease diagnosed as comutant H3F3A and FGFR diffuse midline glioma.

Annals of clinical and translational neurology - 1 Nov 2024

Benistant Larysa, Reita Damien, Schenck Maleka, Castelain Vincent, Cebula Hélène, Lhermitte Benoît, Bender Laura

Abstract excerpt

Diffuse midline gliomas present a particularly intricate and challenging clinical scenario. This rare case involves a patient with comutant H3F3A and FGFR diffuse midline glioma with a clinical presentation of fulminant leptomeningitis. A 22-year-old male presented with fatal and fulminant diffuse leptomeningitis. Next-generation sequencing of plasma and cerebrospinal circulating tumour DNA revealed diffuse...

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Identifiers

PMID: 39440520
DOI: 10.1002/acn3.52180
PMCID: PMC11572734

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